Work package 5: SYNCHROTRON

Innovation within design and manufacturing of complex drug delivery systems (DDS) calls for high-end imaging techniques. Of special interest is the capability of studying these systems in operando – and to study the DDS behavior in situ, e.g. as a function of time, pressure, humidity, temperature and pH, and in both equilibrium and non-equilibrium situations, and to map out chemical composition as well as physical properties of these structures. For such studies, the large-scale facilities offer special advantages.

The high flux and hard X-rays from the synchrotron translates directly into higher spatial and temporal resolution. Neutrons offer the advantage of non-destructive and bulk analysis in combination with unique isotopic information that yields differing elemental sensitivity to that of X-rays. This WP will provide next generation solutions for the visualization of the structure of biological systems and pharmaceutical products.

WP5 is led by Anders Østergaard Madsen from University of Copenhagen.